I've been taking Lamictal 200 mg for a couple of years. I am also hypothyroid, taking 125 mcg of T4 and 25 mcg of T3. My doc wants me to taper off the Lamictal. Apparently I have a hard time losing weight with the combination of Lamictal and hypothyroidism. My doctor monitored a study in which the group gained a lot of weight on Lamictal. He is convinced without a doubt I am one of those people who gain weight and/or can't lose it.

I lost about 30 lbs from Jan. - May 2012 following Weight Watchers, and keeping an intense exercise regimen. I could not keep up the pace of the exercise I was doing. It was primarily aerobic and cardio (Body Pump, Boot Camp, TRX). I did little to none of my former weight training, power lifting style. So I lost a lot of muscle too.

However, after that I began packing on the weight again. It's possible that happened because I was out of commission with a "massive rotator cuff repair" (as the surgeon described it), and could not work out, and fell off WW. However, even when I picked up my workouts again (weights and cardio), and began WW again, from week to week, I had no weight loss.

Now, I'm not as concerned about the scale as I am about the tape measure around my waist... has not budged. Maybe my doctor is right in that I should begin tapering off the Lamictal. We didn't talk about a strategy but I've read it should be very slow, on the order of 25 mg every couple of weeks. For example 175 mg, 150 mg, 125 mg, 100 mg... each dosage for two weeks.

Has anyone else had any of these experiences?