I am not completely buying this article. I am sure everything is factual, it is presentation that bothers me. Here is the disclosure:

"Vladimir Maletic has served on the Speaker’s Bureau or has been a consultant for Eli Lilly and Company and Cephalon. He did not receive any financial compensation for his work on this manuscript. His co-authors are each employees and/or shareholders of Eli Lilly and Company."

There is really only the mention of a comprehensive treatment plan and heavy emphasis on AD's as a lifetime treatment. As suggested this is going into the field of Neuro plasticity. Much research is needed but it is known that ongoing exercise and mindful practices change your brain in positive ways. So if MDD effects your brain similarly then would it stand to reason you could "grow" through natural means?

The particular issue with this article is an AD's side effects can affect your ability to concentrate among other things. Can this not be detrimental and potentially make you dependent on the AD? It is known also that all psychotropic drugs affect people cognitively. And also that coming off an AD can be the cause of a rebound. They can tell based on the type of symptoms you experience between the first one an subsequently.