>>>What medication has worked for depression?>>>

The one that works for YOU! There is no one best medicine, what works for one might not work for another. There are many and they differ in make up, Seratonin, Dopamine, Norepinephrin, mixtures of them, it depends on what your brain needs.

The most important thing is that you have a proper evaluation and correct diagnosis, have a psychiatrist prescribe your meds.and monitor you closely while you are on them. Read about those medications so you will be fully educated about them, side effects, contraindiations, etc.