I have been on Topamax for ove a year know and I lost the over the 17lb avg. wieght fromt eh clinical trials. I do like it i was on the depakote before I i did gain 40 lbs in 6 weeks that is why I went on Topamax. Someone had mentioned something about Ritalin and Weelbutrin and stuff for ADD\ADHD, weel I was on them both at the same time pluys Paxil, and well it wsn't a great combo. But I think Topamax was a wonder drug for me it turned me right around, very quickly too