I feel historically speaking, there's a serious mistrust of big pharm, especially where psyche meds are concerned. If, I were at my laptop, I'd pull some old links to books, etc, when I was sorting through why one family line, nearly staunchly opposed to meds, the other not so much.
Post civil war lit, comes to mind, as does some video treatment of patients in a psyche hospital for showing treatment of schizophrenia.
Ethics, money, lobbying, maltreatment, embedded in oral family traditions and psyches.

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