What time at night do the symptoms start? When do you take your medication? What do you mean by "relapse"?

I have BP2, and I know that I feel more depressed, cranky, and/or have racing thoughts starting ~7-8pm when my medication wears off. These are side effects that I've learned to be aware of and accept. I cope by scheduling earlier bedtimes (e.g. 9.30-11.30pm), because I know that I'm less productive and stable when my medication wears off.