Well, that is not true. Chemical reactions involve only the low-energy stuff.

My objection to the "chemical imbalance" characterization of mental illness is not that chemicals (neurotransmitters) are not involved in every part of it, but that saying so is either trivial, or mischievous, since what people who use that idea are saying, is that the origins of mental illnesses are chemical. They deliberately ignore the fact that "chemical" changes in the brain are caused by experience too. So if you were to have an "imbalance" in the actions of neurotransmitter chemicals, those might have been caused by your experiences (interacting with your genetic makeup), not solely because of broken brain chemistry.

At best, "chemical imbalance" is a tremendous oversimplification of what is actually happening.

Are headaches caused by not enough aspirin in the brain?