I cycle very rapidly and I can't tolerate anti-depressants. I tend to bounce out of depression naturally.

I do have a horrible few days when my meds are being adjusted. Whenever I'm hypomanic and my meds get increased, it feels like I'm driving 80mph and throw the transmission into reverse. It's like a mix of numbness and sadness that lasts for about 3 days and it's horrible. It doesn't feel natural. But that's about the only time my meds cause a depression for me.