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Originally Posted by newtus
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First wow you have such a beautiful voice...second read your earlier comment on supplements....one I would consider is something called sarcosine it inhibits glycine transport thus activating NMDA receptor which typically functions at a lower level in sz. Also did you see where Costello was talking about pregnenolone on nbritton's post....that is also supposed to regulate NDMA receptor levels so you can get more signalling through that path. It's intersting but clozapine and zyprexa elevate pregnenolone levels in the brain and it's though that this might be the mechanism by which they coregulate NMDA helping people who are treatment resistant. So pregnenolone is a steroid and a precursor of all the other steroids so you would want to take too much but if I ever found myself in a spot where D2 blockers weren't working I would likely try one of those 2 before trying clozapine.