yes. I feel a physical difference too like when I am hypomanic I can run for miles lol but when I am depressed I am just soooooooooooooooooooo tired. I also am super organized and detail-oriented when I am feeling good or hypo so that makes it easy to cook healthy food, keep track of what I eat, etc. when I am depressed just getting out of bed is an accomplishment. working out or paying attention to my diet seems like an impossible fantasy dream for another type of person, not me in that moment.