To an extent I agree that certain minor side effects are fairly normal for most meds, and if we stick with them awhile, even those issues resolve. However, some side effects are not tolerable even for short periods of time, and what different people can tolerate varies for many reasons and that needs to be respected.

For instance, I rarely have side effects, and when I do they generally don't bother me much or they go away fairly quickly. But a few times I clearly knew I would not be able to tolerate the side effects. Some people have no problem with a bit of a tremor or blurred vision and will manage with it, but I'm an English teacher. Being able to write and read are non-negotiables for me. My pdoc understands and respects that and works to find different alternatives. Another person who struggles with weight issues in the first place may find weight gain intolerable as it may actually make those issues greater, while someone else isn't bothered by gaining some pounds. As in all things, it is very individual.