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Old Mar 28, 2014, 04:46 PM
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Sometimes psychotic Sometimes psychotic is online now
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Member Since: May 2013
Location: Chicago
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Quote:
Originally Posted by blackwhitered View Post
My mom is a chemist/biologist who worked in pharmaceutical research, so every time I go on a new med, she looks at the structure to see what it's similar to (and thus she can tell what the side effects are likely to be, etc.) She said that blood pressure meds had a similar structure/affect the same receptors as some antipsychotics. She has a theory that some people on these blood pressure meds might have developed psychosis were it not for the blood pressure meds. It's pretty interesting (apparently) if you understand it (which I don't lol.)
Interesting but the D2 dopamine receptor blockade like with APs actually causes high blood pressure so I think it's more likely that the blood pressure meds would act in the opposite way and potentially induce psychosis.

Here is a paper I found on some kidney d2 knock-out mice...

PLOS ONE: Deficient Dopamine D2 Receptor Function Causes Renal Inflammation Independently of High Blood Pressure

So no d2 in the kidney and BP increases....I don't know specifically which BP meds she was talking about though...
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