I have been taking Cymbalta for about 10 months and have only gained 4-5 pounds (that was over December-January, the worst time of year for me). I am feeling a lot better in that I no longer cry all the time and spend way less time ruminating. Sounds like it might be time to talk to your pdoc or gp about changing meds 'cos it's not working for you. Don't give up...the right med can really help your mood.