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Instructions/Best Way to Take Paxil (paroxetine)
Never, ever split, chew, or crush Paxil CR, or the controlled/extended release version of any med. Just swallow it whole the way God and GSK intended. GSK recommends taking Paxil in the morning. Unless SSRIs usually keep you awake, we suggest you should first try taking Paxil at night. I cannot stress how important it is to take Paxil at the same time every day. Because of its short half-life and non-linear pharmacokinetics 5 it’s easy to understand, or at least wrap your head around the concept of why some people can get SSRI discontinuation syndrome if they are a few hours late taking their dose. With Pexeva and other branded generics that are paroxetine mesylate, you have some wiggle room. You can’t miss a day, like you can with Prozac or Abilify, but like Lexapro if you’re a few hours late you probably won’t notice anything. ~ crazymeds.us
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