I don't know . . . I'm on my third AD now - - first viibryd, then Prozac now wellbutrin for a couple of weeks (but I think I was on wellbutrin in the recent past from a different doctor too). So far, the wellbutrin is not helping at all. I'm starting to wonder if anything ever will. I'm coming up on 8 months in this bipolar depressive episode. It really sucks. Too scared to try ECT.