I can understand your frustration with some of the responses you recieved, but ultimately, I had the impression from your initial post that you were looking for opinions, not just positive stuff you want to hear. I know as someone who has some chronic health issues myself [not just mental issues], it can be exciting to come upon something that has promise, and very frustrating when we start getting negative feedback about a treatment or therapy we were feeling positive about.

The thing is, you asked for opinions, so you will generally get responses that include every kind of opinion.

I think the responses regarding validity and reliability- two very specific terms when speaking of research- may be referring to the fact that the only thing you cited was from 1935. So, people who rely on recent studies that are peer reviewed- which are often considered to be the most valid and reliable- are not generally impressed by outdated material. That is not to say what you cited is completely nonsense- but if it is still accurate information, it has likely been redemonstrated more recently.

Google Scholar is a great place to look- one can be very specific about subjects and year and there are many free access peer reviewed articles available. Pubmed is good as well. Harvard, Johns Hopkins, and other large universities [I'm not as familiar with which ones might be most helpful where you are] often have access to research resources somewhere within their offshoot med sites, even if you aren't a student. These are some of the places I look for information to consider when thinking about a treatment or therapy and if it may benefit me.

I can't speak for those who were critical, but conductivity is not in question in my book. I have seizures, which are kind of a freakin' electrical storm in the brain. But intercellular fluid is mostly potassium and sodium along with other trace elements [as in sodium/potassium channels]... and while gold is a great conductor, a lot of things need to be done for the gold to actually be helpful, in my opinion.

The blood-brain barrier is very selective, for example. It doesnt just let anything. So not only do the gold particles have to be small enough, they have to be disguised in a way that will induce the blood brain barrier to let them pass- and then the way they are disguised can't interfere with any good the gold particles could possibly do.

This process doesn't sound like a cheap one?

Nanomedicine is really in its infancy. There may be in theory all kinds of uses for colloidal gold, but the logistics of it may be just out of reach for real results. But that could just be now.

I know that some of the strongest ideas running right now for it are to be able to use it in cancer treatment.

I don't have lyme, but some of my symptoms are similar.
I don't know what you have tried thus far.

I've personally found fish oil [high grade, no vit a, etc] in high doses to be helpful, but that can take a while to kick in.
My vitamin D is low and that can be pretty brutal. An imbalance of certain B vitamins- in particular B6 and B12- can affect nerve pain and other types of pain.

I'm not one to subscribe to solely non-pharm approaches *if* I feel the pharm approach is helpful as well- I do think there is room for pretty much anything that helps. We have to be careful about possible build up in our bodies of certain elements, particularly if we have a pretty chronic condition. Long term it's hard to always predict what the results could be.

I can't say either way whether colloidal gold is the way to go. I personally feel right now there may be other things you could try that have progressed further and might not be as expensive, may have a little more evidence to back them.

I wouldn't try it, not now. In the future, as understanding of possible advantages or disadvantages to the therapy increases, I would consider it.

Another thing to think about is there are different things that could be referred to as colloidal gold, and "colloidal gold" of 70+ years ago is not the same as that of now.

But I mean, if you are considering putting something in your body? I would certainly start at academic research [from a variety of sources- not just one] to get a feel for if it may be right for you. If you feel good about it and get a go ahead from a provider who is up on all your meds... there really wouldn't be any harm. If it doesn't end up helping, than at least you have eliminated one more possibility- you've narrowed the field of things that might work! So it's still a success.