Quote:
Originally Posted by WeepingWillow23
Have fun!
Idk about the specific med you are on, but I was told in pharmacology class that unless a tablet has a indentation across the middle (which makes it easier to split in half), you shouldn't cut them smaller. This is because in ones with the indentation, the manufacturer has guaranteed that the active ingredient is equal in each half of the tablet, so it can be cut. Otherwise the active ingredient is unevenly distributed throughout the tablet so splitting them in half doesn't give you equal medication amounts in each half.
*Willow*
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I'm really not sure what could cause uneven distribution of medicine in a pill...seems like an odd concept to me I mean they make a big batch and then make it into pills the whole batch had to be evenly mixed in order to get even doses in all the pills. The thing is with APs they are in your system for a while I don't know for Latuda but for abilify the half life was 72 hours so even if you got a little less in one half you'd still get the full dose when you took the next half 24 hours later. Abilify definitely did not have a split mark but was stated OK by my pdoc for sure and no warning in the 6 page guide although there was one for the oral dissolving tablet. I'm wondering if this could be a UK vs US thing...do you guys make pills that have like stripes of ingredients? That's the only thing I can think because normally there is sort of an extruded tube and then they get sliced into rounds sort of like an egg slicer would do...you know for the classic pills for the fancy ovals and stuff I have no idea...I pretty much assume they are molded in which case distribution should also be uniform...
Here is a list of uncuttable meds...most are due to enteric coating or extended release formulations...
http://www.ismp.org/tools/donotcrush.pdf