See, this is what makes it all highly individual. I am on Lamictal 200 mg, and Wellbutrin 450 mg, and at 56 y/o I am as horny as a teenager. Wellbutrin is supposed to be the least likely to cause sexual dysfunction. Lexapro was the worst for me. While I had the drive and ability to maintain erections, I couldn't *ahem* finish. It was most frustrating. Doc took me off it. You and your doc may have to experiment. Unfortunately one size does not fit all (isn't that always the case?). You might want to have a male hormone panel done... testosterone, estrodiol (we guys do produce estrogen, and it can put the brakes on testosterone), and SHBG (sex hormone binding globulin). Low testosterone (anything below 500-600 is not normal, so don't let your doc tell you that your testosterone of 253 is normal) will cause brain fog and moodiness. I use Axiron testosterone, which keeps my levels between 500-700.