I get really nauseated when I don't sleep too, but that doesn't stop it from happening when I'm manic. I can go a week or more with maybe a two hour long catnap per day. If it's no sleep at all, 3 or 4 days and by then I'm likely so manic I'm psychotic. And because of the nausea, I don't eat much. It's not abnormal for me to drop some weight during a manic episode.

Sometimes lack of sleep will SPARK a manic episode. I was volunteering for a week or so at a music festival and because we were short staffed, there was only time for about 3 or 4 hours of sleep a night. After 3 days of that I was hypomanic. I was a crazy productive worker and won the MVP award, but also crashed and ended up letting my supervisor know what was going on.