I don't know. I've learned to accept that the depressions cycle in and out and up and down, and I've also learned to predict and anticipate that those cycles indeed DO cycle and there will be real relief if I can maintain some perspective and patience with myself and the whole damned process. I have much less utter despair now than I used to, and that is encouraging. I have more stamina through the episodes of depression than I once did, in great part to therapy with immense help from successful meds.