You did say that you have been diagnosed with depression so assuming you have adequate energy to function I would like to suggest doing things outside of your routine that involves other people. By isolating yourself, you are leaving yourself available to:

1) not engage in activities that take your mind off of your current state. When you increase you abilities in an area you hopefully get a sense of accomplishment. This is even mores the case when the activity involves around helping others or achieving a tangible, objective goal.

2) You aren't meeting new people. Not everyone is out to get you and the more you isolate yourself away from people. If you don't give yourself the opportunity to have people prove you wrong (in that they are to be avoided) you just sink more and more into isolation. I'm not saying you do have to be popular. It is perfectly fine to not have tons of people around you. It's alright to enjoy activities alone. But you need to be able to have people who care and accept you for who you are and they do exist. There is NOTHING and I repeat NOTHING wrong with you inherently that makes you automatically dislikable.