For me it is taking a cocktail of meds daily. It has been a 5 year long battle to find some that work for me. I can finally say that after five years I have finally achieved a life I feel is worth living. It's been about 3 months now and this is my cocktail
Prozac-60mg
Dexedrine-40mg
Nuvigil-250mg
Remron-30 mg
Latuda-80mg
Suboxone-4mg
It's been a very tough road but I finally feel it was worth the fight. 45 med trials later
and this is where I am and managing well now-Thank God.
If you notice, I am on two amphetamines which are so crucial for me. If I am without them, I can't even leave my house. They were my saving grace to allow me to go back to work full time. I find them to be a wonderful antidepressant, but it can be tough to find a Dr. that isn't afraid to use them like this. I am lucky-mine swears by them for me.
I also find that a med I am taking for an opiate addiction-suboxone-has also prooved to have antidepressant qualities. When I had started a taper off it I really tanked so my Dr. stopped that process immediatly and all was well again.

Eventually, I would love to say I can whittle this drug list down. I am sure it is hard on the body. But for now, this is what I require and I am so very much grateful to not be living in the hell that I was before.