I was on it for awhile until the side affects got to bad for me to handle. It didn't really make me tired. I was taking 250 mg 3 times a day. Some people can handle it better than others.

I would notify his proscribing doctor and voice your concerns. It may be interacting w/ other meds or certain foods in his diet.

As for the weight gain, I never did have that problem, but even in my worst depression, I have always been very active. It drives my pdoc nuts.

Good Luck, and I'm glad he has someone that cares.