That's a tough situation you're in but something has to give at some point. Not all SSRIs are equal, as I am sure you know. Celexa was great for me but Lexapro wasn't helpful at all... And they're supposed to be similar. It's weird how drugs work for different people. I would say get a genetic test if you can. I didn't have great luck with it but it at least gives me the piece of mind that I'm trying drugs that my body might metabolize well.

If that is not feasible then if I were in that position I would definitely try a different drug but maybe a different kind of AD. Have you tried SSNRIs? Those might be better for you. Although would be best to talk to a pdoc about it first even if that means getting an appointment with a new one. It's better to have their guidance as they are the pros.

Hang in there and don't give up because medication can help take the edge off and even if it's just a little, if the side effects are not bad, it could be worth it.