I concur.. meds can and do suck. I have been on a few ssri's in the past and recently felt the need to go back on something after a decade off. My therapist thought depression was hindering me. I also wanted to relieve some social anxiety and gain some motivation and confidence to tackle some problems. Tried Wellbutrin (ndri) and then zoloft and then both in combination. Nothing but various side effects including worse depression and SI even. I am off everything now (2 months) and am finally starting to feel normal again. I guess my level/type of depression just doesn't lend itself to meds. I've been told the greater the level of depression, the more likely meds will help.