Quote:
Originally Posted by thepterodactyl
It's true the slow titration significantly decreases risk (so does being post-adolescent), so it is about 1 in 10,000. To someone without health phobias it would seem to be worth the risk, but unfortunately that is not me. It is true that once you show signs of the rash - if it's SJS and not a much more common mild allergy - there is nothing you can do but let it run its course and treat the symptoms. Even if you stop the meds right away it's still going to do it's thing, which is unpredictable. I am definitely NOT trying to make a case against lamictal based on this - I realize I am being totally irrational - but the rash fear is reason enough for me to avoid it, only because it triggers major anxiety (when I took Zyrtec for the 1st time I did it the parking lot of an emergency room "just in case" - that gives you an idea!)
Perhaps if they tranquilize me with something first and then feed me the lamictal
I managed to schedule an app. next week with a difference psychiatrist who is rumored to be much more understanding and open-minded...hopefully she will have some ideas, but I really appreciate everyone's comments!
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Then I think is a good idea to avoid some other medications that can cause SJS. This includes the following in particular: Anti-convulsant like Carbamazepine, Valproic acid, Lamotrigine, anti-inflammatory like
Ibuprofen, antibiotics like Sulfonamides,
Penicillins and so forth. All of the above meds have SJS listed as a possible complication.
I hope this helps!
Stevens Johnson Syndrome, Toxic Epidermal Necrolysis. SJS/TEN. DermNet NZ