I've heard of a double whammy, even a triple whammy, but I'm up to a quadruple whammy

1: Depression
2: Meds making underlying physical condition worse, so doc reduces dose of a/d - Depression deepens
3: Second physical condition results in severe anaemia and associated Depression
4: Meds to treat new physical condition cause (you've guessed it) Depression

I am so unhappy, but being able to care about that unhappiness is beyond me. Maybe if I don't take my new med, I'll eventually bleed myself into oblivion. Would a DNR notice count if it was written whilst depressed?