I suffer from BP 1 mixed episodes and go through the exact same thing. I will go from being irritated, energetic, etc. to just down right depressed briefly and then back again to the mania. I have been through numerous meds, but I finally found the right combo. I recently came off of Seroquel because my sugars and triglycerides were through the roof and it wasn't working, and now I am on Haldol. I feel great.

BP 1-mixed episodes/OCD

Lamictal 400mg
Haldol 4mg
Klonopin 1.5mg