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May 20, 2014, 01:37 PM
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Member Since: Oct 2013
Location: Texas
Posts: 340
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Quote:
Originally Posted by WeepingWillow23
I'm not convinced both groups were the same if their SANS scores differed by 15 points to begin with. Then they both drop the same, so it's ?placebo. I'm interested in TMS from a depression POV, but I get the impression that it's not done in the UK outside of any research trials. Also, I worry about the side effect profile as it's not been studied long term I don't think and problems may only appear 10 or 20 or whatever years down the line :/ It definitely sounds less invasive than ECT though, which is good.
*Willow*
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One of the studies for minocycline (an antibiotic typically used to treat acne) noted a 9 point SANS reduction. I've been on it before, to treat acne, and did notice an improvement with my psychiatric symptoms, in general my mind felt less cluttered, I was able to think better. At the time I didn't know minocycline had this effect, so I didn't attribute the improvements to the drug. Now that I know, I'm going to ask if my psychiatrist will prescribe it...
Minocycline benefits negative symptoms in early schizophrenia: a randomised double-blind placebo-controlled clinical trial in patients on standard treatment.
Chaudhry IB, Hallak J, Husain N, Minhas F, Stirling J, Richardson P, Dursun S, Dunn G, Deakin B.
J Psychopharmacol. 2012 Sep;26(9):1185-93. doi: 10.1177/0269881112444941
A double-blind, randomized study of minocycline for the treatment of negative and cognitive symptoms in early-phase schizophrenia.
Levkovitz Y, Mendlovich S, Riwkes S, Braw Y, Levkovitch-Verbin H, Gal G, Fennig S, Treves I, Kron S.
J Clin Psychiatry. 2010 Feb;71(2):138-49. doi: 10.4088/JCP.08m04666yel
Last edited by nbritton; May 20, 2014 at 02:03 PM.
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