I personally didn't like Latuda much. It didn't work all that well and was super hard on my stomach (I puked 1-2x per week due to not having enough food in my stomach). When I came home from school and switched pdocs again, I asked to be taken off it, and I went back to Seroquel which I have been back on very happily since the end of last June. I also became manic in the time I was on it, and while I can't say for sure that it was from being on Latuda since I switched ADs at the same time, I believe that it happened because of the Latuda since only one AD (Zoloft) has ever made me manic, and that was before my BP Dx so it was the only med I was on at the time, and I have happily been back on that for almost a year as well.