I hate the weight gain. Before going on psych meds, I was 5'10" & from 118-125 lbs. Too skinny. I had wild energy (super manias) & could do 10 projects at once (at work) & dance 3 hours/night, hike, run etc. On the meds (Depakote for manias & seizures, Seroquel for insomnia/hallucinations), I gained 50 lbs. My doc told me not to worry about it, since my BP & other readings are normal (altho' both meds can elevate your glycemic index). I HATE the weight gain. I dance but do not have the energy to dance more than 15 min. at a time. I walk 20-30 min. 3-4/week (if weather is OK), I do yoga, sit ups, etc. & still am fat. I pray every day that scientists will figure out a psych med that does Not slow down your metabolism & cause major hunger!!