I just want to respond by saying, " I have been on them all" !! I was on seroquel @800Mgs per day. Saphris 20mgs BID, And remeron, , Lithium, "Witch is HIGHLY TOXIC". 600mgs, and everything in between. I am now on Neuronton, Depakote, and just went off Trazadone. The meds they give you can have PROFOUND effects, But, only you know your body, diet, and what it will allow. I am also on a Controlled substance called, " Klonipin", Wich I told My P-Doc, should be a felony to prescibe. The problem is, and some of you might not realize, Scientific Term, Clonazapam is a NARCOTIC !! Plain, and simple. That is NOT a prn , as some might think. Your body does become deppendant on it, and you suffer. I deal with GAD, ADHD, Bi-POLAR, and other issues called PTSD. This is not a battle that can be won without a PLAN !! Welbutrin was awesome, as well as Paxil, (given some side effects for male's), I loved Seroquel, as it helped shut down my Mania, But, Given sientific research, It does cause DRASSTIC weight gain, and also rise's your Trigliceride's. I am kinda , a walking med Cabinet, so if anybody wishes to talk about meds, and there side-Effects, Please, Feel free to contact me here on site as Guy w. I love to talk about meds, and there side effects. I wish all of you with Bi-Polar, The best, and guess what? We are TRUELY< The most gifted, yet miss-understood people on the planet !!! Go ahead, look it up, and see, it is very true. Bye now to all, and have a fantastic week-end ! Sincerely, Guy W.