I have had the most disturbing dreams of my life with Seroquel. About six months ago I started on 50mg of Seroquel as a sleep med. I was on a ton of other meds at the time, and was also undergoing ECT.

Then 5 months ago I switched up everything; stopped ECT, upped Seroquel to 200mg as a mood stabilizer, cut all the rest of meds except 100mg of Zoloft and 50mg of Lamictal (which I was intending to eventually increase as a way to replace Seroquel). I also take 20mg of Buspar occasionally on an as-needed basis for anxiety.

I am a 5'8" female and at the time weighed between 105-120lbs (it varies a lot). But either way I believe the 200mg dose of Seroquel for someone of my size (who was not intending to use Seroquel as an anti-psychotic) was kind of a high dose. I was ZONKED OUT. So exhausted all the time, although admittedly getting much better.

During this period if someone tapped me to wake me up, I would wake up with a scream. I never felt that I was having nightmares though.

For the last couple of months I have been reducing the Seroquel, and am now down to 25mg. As I started reducing I began noticing that I was having incredibly vivid dreams. Most of them are not nightmares (I don't wake up breathing heavily or with my heart racing and adrenalin pumping) but I find this incredibly disturbing. I have started to have trouble sleeping and so decided to go back up to 50mg one night to get better sleep. Instead I had the most disturbed sleep of my life. My dreams were so vivid and realistic that they felt more real than actual life; I woke up feeling that I had been awake all night because I was so present in my dreams. Real life seemed flat and comparison and I felt very unsettled and upset by this all day.

I usually take my anxiety med (Buspar) before going to sleep now and that seems to help somewhat. I don't have a history of hallucinating, and have never really even been able to remember dreams in my life so this is pretty out of character for me. I suspect I first started becoming aware of the dreams when I began tapering down the med because I had been so knocked out before I was too out of it to notice or remember the dreams.

I know it sounds silly (being so scared of dreams that aren't even nightmares) but I've just found the whole thing incredibly disturbing