I gained 40 pounds on seroquil, and it also gave me quite vivid dreams. I was taken off of it and put on abilify, which I like much better (not because of the weight side effect). I've been on lamictal for almost as long as abilify, which is about 16 months, and I hate it! It helps control my ptsd symptoms, but the side effects are terrible for me. But I love prazosin; I had ptsd nightmares for so long that I would be afraid to sleep and I stayed up for three days and four nights until I was hospitalized. The prazosin has been life changing for me.
If you feel that seroquil isn't helping as much as it could, talk to your pdoc about it and the symptoms. Its really all about trial and error until you find the right meds that work for you.
I hope you find your best combination

pm me if you'd like to talk meds more
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