I'm a 31 year old female dealing with major depressive disorder and panic attacks. I have been on antidepressants for almost 10 years now. I have tried almost every kind of medication. I was on Lexapro 30mg for a long time and still having severe panic attacks. My psychiatrist and I decided to try Zoloft. We cross tapered the meds over the span of 10 days. It has been 2 weeks since the beginning of the cross taper and most days have been good. Today, however, was rough. I felt light-headed and in a fog. I am lacking motivation and feeling very tired. I got into an argument with my boyfriend over something stupid and cried for almost 3 hours. I have some intrusive thoughts but no plans to hurt myself. Do I just need to give the Zoloft more time? My doctor said it may take three weeks for the new meds to kick in. Is this the Lexapro leaving my system?