As much as a biological/chemical issue is rooted in depression, my doctors have stressed to me how much CBT (and DBT) is critical for bringing me out of the dregs. As much as I would like to get a "bump" from medication, my therapists and pdocs (all of them over the years) have stressed that it's critical for me to lay down new ways of thinking.

I, too, come back with clean blood tests all the time and I recently refused to have a test to see what kinds of drugs I metabolize best based on the information I found on this forum. Many people have found that those tests come back with information that is not always that helpful, so don't be discouraged if you get back test results which does not tell you in big flashing letters "ah ha! This is the cause!" It won't be like that.

It sounds like you are anticipating that your blood work is going to going to come back with no information and that will be a set back. Try not to look at that way. No results is not an indication of negative results, it's just one more piece of information. So you tried bloodwork...okay, so at that point you can cut bait and move in a different direction.

If you have ever seen the TV show "House" you'll see that House never gets discouraged by lack of results, it means he hasn't found results to support his hypothesis.

I hope this helps, hang in there.