Mapper, I can sympathize. I had a boyfriend like that. The man never had an un-uttered thought. We did not last long at all. As annoying as she is, be thankful that you do not have to live with her. I don't know what drives people to talk all the time like that. They seem to have absolutely no clue how their behavior affects others. The part of their brain that regulates social behavior is wonky.

Unless you need to converse with her on work-related matters, my advice is to ignore her. You're not being rude. She is being rude by commanding people's attention every minute of the day. You need to get work done. If she asks why you don't respond, just say "Hunh, what? I'm sorry I was concentrating so hard on my work that I didn't hear you. What do you need?" If she talks about something that's not work-related, just say, "Oh, okay. Well, I need to get back to work. Nice chatting with you." Yes, she will persist even more for awhile, so hang in there! Most likely, though, she won't change her behavior. You can only change how you respond. Not fair in this situation but you don't have many good choices. In the meantime, enjoy the respite from her.