I think it depends on how biologically and genetically the causes are. I think in my case it is very biologically genetically ingrained. That doesn't mean non med techniques don't help.

This is just my speculation but it seems if someone who does not have a biological disposition to depression and it was caused by trauma in child hood or whatever, all environmental, would stand a better chance with therapy alone if they chose not to use meds.

I did all kinds of therapy and AA for many years and my depression has gotten worse as I have gotten older. I like to think I resolved all my past situational issues through that yet the depression persists. It is frustrating.

Unfortunately the meds are just not that effective many times. I think big pharma made some steps in the right direction but there is a lot more to it.