I have never heard of a doc prescribing opiates for depression and I don't think one ever would.

I am a recovering drug addict and alcoholic so have some experience with opiates. I have to say they are the best anti depressant I have ever taken. However the addiction and withdrawal from them is not at all worth it. You don't have to have an addictive personality to get addicted to opiates.

I would advise the whole world to stay as far away from opiates as possible except for pain management which is what they are for.

Some docs do prescribe amphetamines in rare cases for very treatment resistant depression. Taken only as prescribed and no more as they have a high potential for abuse.

If you are trying to self medicate with street drugs like sub or vicodin or benzo's or amphetamines it is a rather dangerous path. I am not saying it can't be done with much discipline. It would seem a very expensive way to go also. And can you always have a reliable source?

I would advise working with a psychiatrist but they won't give you opiates. They will give you the standard ones and try different ones. They have there draw backs but not like opiates, benzo's and amphetamines from the street.

I have actually tried vicodin for depression and it worked quite well. (from the street) The problem was tolerance build up. Very quickly went from 2 or 3 a day to 5 or 6. When I couldn't get anymore from my source I went through horrible withdrawal that made my depression much worse. Sub is not really any different. As much as I would love opiates for depression there is no way I would go there.