I've been on microgynon for about a year and haven't noticed any relation between the pill and my depression. I was also prescribed anti-depressants whilst on the pill and the doctor didn't seem to think this was a problem at all (and it wasn't). I think you should go back to your doctor and really emphasis how you feel, like you did in your orignal message. You could also try to stop the pill for a period of time to see if your mood levels out and then you'd have your answer.