I think part of the issue is that while the website might be reliable, sometimes the distributors that they use are not.

They replace actual pills with sugar pills or something else and pass them off as brand. It is the 'something else' that worries me. I'll give you an example.

A friend of mine wanted to buy Xenical on line and I gave her a website that I thought was reputable and had used before. She bought a two month supply and took them for about a month. Nothing happened but she later learned that the pill looked pretty different from the 'real' pill.

She took it to a pharmacist who said that yes the one she bought was probably not the real Xenical. I felt so terrible. Luckily, nothing happened to her but something could have...