Interesting. It's not too suprising to me that AD's can change the menstrual cycle (mine hasn't been changed by depression, but I just finished my first cycle on AD's and it began 2 days early, and was 2 days longer than usual, what a pain to have a 9 day period) seeing as the AD's are changing your brain chemistry, therefore changing your body chemistry. Many hormones play a role in when you ovulate, and finally menstruate, so I guess I wasn't too suprised to see "menstrual changes" listed as a side effect.