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Originally Posted by ChangingMyMind
Thanks metamorphosis12,
It's actually only one brand that does it so I did stop taking that brand. It was the 365 brand that did it. I now tale Jarrow without that problem. Although I think it constipates me it's the only option I have right now.
I am not taking and other drug that would interact with SAM-e. Especially Any other antidepressants. I've been taking a very low dose as well 400mg and pdoc is aware. I do appreciate the post and concern.
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Jarrow is a well respected and affordable brand. I have not seen one of their supplements rejected on consumer labs and other testing facilities. Here's a link to how important it is to have a good brand with blister pac. It's just a basic article put is spot on for the reasons that thee are a lot of brands that fail
How To Choose SAM-e Supplements | Health Supplements
Can't beat well regarded College studies!
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Available Forms
SAMe is available in tablets or capsules, which are more stable and may be more dependable in terms of the amount of SAMe in the pill. They should be stored in a cool, dry place, but not refrigerated. Tablets should be kept in the blister pack until you take them.
How to Take It
Starting with a low dose (for example, 200 mg per day) and increasing slowly helps avoid stomach upset.
It is important to note that many of the studies of SAMe have tested injectable, not oral, forms. It is not as clear how reliable or effective taking SAMe orally is. Small studies suggest that oral supplementation with SAMe is not well absorbed by the body. Clinicians recommend taking oral SAMe with vitamin B12, folic acid, methionine and trimethylglycine to enhance absorption.
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University of Maryland Medical Center
S-adenosylmethionine | University of Maryland Medical Center