Hi, I am on topamax 300mg, serequel 400mg, lunesta 3mg, these are all taken at bedtime. I was taking valium 5mg , once in the morning and once in the afternoon. I had my appointment with my doctor this past Monday. He said I seemed a little anxious and looked somewhat wired through the eyes. I told him that I had been feeling quite anxious during the day and was having racing thoughts that were getting more frequent. He changed my valium to 10 mg during the day. One in the morning, and one in the afternoon. My manic takes over the depression. I guess I should be thankful for that. If something bad happens I do get sad, but I don't go into a deep depression. This is a terrible disease, at least to me it is. You never know what is going to happen, or when the manic is going to hit. I once forgot to take my nightime meds and the next day was a day of total havac. I never want to go through that again. Sorry so long. Just trying to get my feelings out about this.