I had a major depressive episode about three years ago now that resulted in me being hospitalized (they did nothing for me while I was there) and ever since I've pretty much lost all interest in everything, including things I love. I also do not feel anymore, I don't feel depressed, I don't feel happy, I just feel "there". I've been tried on just about every SSRI there is at maximium dosages with no effect, my doctor is now trying me on a SNRI (Effexor 225mg) and that isn't making any difference either. I also cannot focus to do anything such as reading or studying, which is going to be a problem because I'm planning on starting college in Spring of 2015. She tried Ritalin 20mg SR and that did nothing for me and I'm now on Adderall 10mg which is doing nothing. I've had severe insomnia since I was about 14 (I'm 32 now) and treatments were helping it but now nothing seems to help, I'm currently taking Seroquel 400mg, I take it around 10pm, lay down around 11pm, finally fall asleep around 12:30-1am and wake up 6 or more times a night. Something new has started with sleep medicines here lately too, just about everyone I've tried, they cause severe RLS. So far Seroquel is the only one that responds to RLS treatment, requip at 3mg. I also have anxieties and have been tried on many different medicines with no effect.

What can I do, suggest to my doctor, whatever that will help me function again?