Hi, I'm new to this site but not new to BP. I'm 46 and was diagnosed BP1 when I was 19. I was put on lithium and though have tried different anti-depressants for short times- have never found one that worked or actually, one I could handle the side-effects of- so it's been me and lithium for 27 years. After months of increased urination, I went to my GP for tests and she's come back with a diagnosis of diabetes insipidus. I've stopped crying for the minute to write this and ask for advice. I'm terrified- beyond terrified. I haven't had a psychotic break in 25 years - I had a hard time accepting my diagnosis and was reluctant to take the lithium but lost reality and ended up psych wards 4 times. My life was totally destroyed those 4 times - did all of this without any support from friends (lost them with diagnosis and acting "weird") or family. We all know lithium has little affect on depression and have rolled with mine as best I could but now I'm so scared. This diabetes insipidus isn't reversible and I know the next move is to go off the lithium but I also know nothing is as affective in controlling mania- the beast has been at bay for 25 years- I can't have it back. So after my rambling- here are the questions: Has anyone out there experience diabetes insipidus? Long term lithium use? Anyone have had manic episodes that are complete psychotic breaks and use an alternative to lithium? One that doesn't cause weight gain? (my life stabilized so well that I felt brave enough to take off the 125 lbs I need to lose and have lost 52 already!) Thanks to everyone taking time to read this.