Being manipulative to people to get nurturance is one of my strongest BPD traits. It probably comes from surviving child abuse. That might not be your friends situation, though.

Setting boundaries with people is very important in any relationship. If you're comfortable, I would GENTLY tell your friend that their behavior is tiring you out. Please make sure you are gentle with them! In my experiences with being called out on my manipulative behavior with others, the gentler the better. It's easier for the other person to understand your needs and that you still care about them.

Also, please keep in mind that your friend probably doesn't know that they're being manipulative. Most people with BPD/BPD traits are manipulative only because they feel like it's the only way to get the attention they need.