At the moment I can't tolerate more than 50mg slow release at night and leaves me with a constant feeling of tiredness throughout the day. Was on 200mg at one stage and slowly weaned down. Sure 4 years ago I was on a much higher dose but I was completely manic so I didn't have the hangover effect the next day. Personally I wish I didn't have to take it but recon I'd never sleep without it. Lack of sleep used to be one of my hallmark features when beginning to go hypo now I have to look for other symptoms because boy does it make me groggy.