I wish I could answer your questions about your b/f's possible symptoms or withdrawal, but I'm also wondering why he ran out. Surely his r/x was for one month? And, just so you'll both be aware, I think it's possible to renew a subscription 5-7 days before the renewal date on the bottle. Medicare Plan D allows this, but I don't know if all insurance does. I always, always do this, so I have plenty of extra tablets most of the time.