I drink pretty frequently, and not just 1 glass of wine either, since to me the whole point is to get at least a buzz. I'm generally pretty good about not taking it too far and getting sick/passing out, though. I don't find that alcohol makes me depressed. When I drink I actually get kind of hyper and hypomanic and generally feel fine the next day.

I know you're not "supposed" to drink with meds, but no one has ever really given me a good explanation of why. I avoid taking my Stelazine when I drink because the combination makes me dizzy, but I always take my Zyprexa at bed-time. Because alcohol is a dopamine agonist it may make the Zyprexa slightly less effective, but that's not dangerous. Both my Dexedrine and cigarettes are also dopamine agonists and nobody says I can't take those with Zyprexa. Alcohol's major effect is as a muscle relaxer and GABA inhibitor, identical to benzo class drugs, which I know are safe to take with anti-psychotics.

I guess I pretty much view alcohol as another anxiolytic drug that I can use whenever I need to.